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Phentermine is not recommended for patients with symptomatic heart disease including rhythm problems. Phentermine is sold either as an immediate-release formulation (Adipex®) or as a slow-release resin (Ionamin®, Duromine® in Australia and New Zealand). A dose taken too late in the day can cause insomnia. In fact, generic and brand name phentermine together account for about half of the total prescription appetite suppressant sales.

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